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Psychiatric disorders associated with increased risk of colorectal cancer in the UK biobank cohort.


ABSTRACT: Psychiatric disorders are associated with several cancers. However, data on the association between different types of psychiatric disorders and colorectal cancer (CRC) are scarce. The aim of this study was to determine whether there is an association between psychiatric disorders and CRC using UK Biobank. We excluded participants with a previous diagnosis of cancer (except non-melanoma skin cancer) prior to baseline and conducted a matched cohort study with new-onset psychiatric disorder patients after recruitment as the exposure group and matched non-psychiatric disorder individuals as the reference group. Through UK Biobank, we obtained clinical diagnoses for the psychiatric-disorder patients from their hospital records. The Cox proportional hazards model was used to estimate the hazard

SUBMITTER: Wang Z 

PROVIDER: S-EPMC12800037 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature