Chromosome-resolved genome assemblies of Rhodotorula toruloides reveal abnormal chromosomal evolution under artificial culture conditions.

ABSTRACT: Rhodotorula toruloides is a basidiomycete yeast known for accumulating lipids within its cells. Owing to its oil-producing potential, many strains of this species have been isolated and studied. However, substantial genetic diversity has been reported within this species, making the true taxonomic boundaries of R. toruloides ambiguous. In this study, we sequenced the whole genomes of multiple strains of R. toruloides and related species, generated complete chromosome-level assemblies, and conducted comparative analyses. We found that the genomes of Rhodotorula and Rhodosporidiobolus generally comprise 17 chromosomes with conserved chromosomal synteny. However, some strains of R. toruloides exhibited chromosomal shuffling. Notably, several of these rearrangements were observed among strains

SUBMITTER: Kobayashi Y 

PROVIDER: S-EPMC12800127 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature