Molecular competition induced Janus hydrogel bioelectronic interface for electroceutical modulation.

ABSTRACT: Janus hydrogel bioelectronic interfaces have long been challenged by complex fabrication procedures, poor controllability of asymmetric properties and weak interlayer bonding strength. Herein, we fabricated a Janus hydrogel with dual structural and compositional gradients in one step via Molecular Competition Induction mechanism. Unilateral UV light-driven competitive reactions between distinct monomers induce spatiotemporal progressive polymerization, facilitating heterogeneous distribution of polymer segments and gradient-structure formation. The unique configuration effectively addresses issues of weak interfacial bonding and interlayer slippage in Janus hydrogels. Associated with the programmed directional (upward) migration of adhesive groups during fabrication, the Janus hydrogel ach

SUBMITTER: Qu X 

PROVIDER: S-EPMC12800210 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature