Implementing a fully computed tomography-free online adaptive palliative radiotherapy: a one-visit workflow.

ABSTRACT:

Background and purpose

Same-day palliative radiotherapy requires rapid workflows, but conventional computed tomography (CT)-based workflows cause delays and strain resources. Advances in cone-beam CT (CBCT) enabled accurate dose calculation and planning without a planning CT. This study evaluated the feasibility and efficiency of a fully CT-free online adaptive workflow for same-day palliative radiotherapy using high-quality CBCT.

Methods and materials

This prospective study enrolled sixteen patients between January-May 2025, of whom fifteen completed same-day treatment. Eligible patients were referred for single-fraction palliative radiotherapy (8  Gy) to non-mobile target volumes. No planning CT was acquired; instead, a reference plan was generated on a phantom with standa

SUBMITTER: Jaglal AT 

PROVIDER: S-EPMC12800496 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature