Atrial fibrillation laser balloon ablation: Multicenter international study.

ABSTRACT:

Background

Durable pulmonary vein isolation (PVI) for atrial fibrillation (AF) remains challenging. The visually guided laser balloon (VGLB) is a unique single-shot technology designed to simplify PVI.

Objective

This study aimed to assess the real-world safety and long-term effectiveness of the third-generation VGLB system for treating paroxysmal and persistent AF.

Methods

This prospective, multicenter registry enrolled 427 patients undergoing VGLB-PVI. Safety was assessed in all patients, whereas the primary effectiveness endpoint (12-month freedom from AF) was analyzed in 392 patients who completed follow-up. Cox regression models were used to identify predictors of recurrence.

Results

Acute PVI was achieved in all targeted veins. The system demonstrated a fa

SUBMITTER: Martignani C 

PROVIDER: S-EPMC12800799 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature