Left Bundle Branch Versus Apical Pacing in Atrioventricular Block and Normal Cardiac Function Post-transcatheter Aortic Valve Implantation: PhysTAVI Trial.

ABSTRACT:

Background

There is currently no evidence of the best pacing mode for high-degree atrioventricular (AV) block occurring after transcatheter aortic valve implantation (TAVI). The objective of this pilot study was to compare a clinical combined endpoint achieved by left bundle branch pacing (LBBP) vs right ventricular (RV) pacing in patients with preserved left ventricular ejection fraction (LVEF) post-TAVI at 12-month follow-up.

Methods

Consecutive patients post-TAVI with high-degree AV block and LVEF ≥ 50% were randomized to LBBP or RV pacing. The primary endpoint was survival with an improvement of ≥ 1 point in New York Heart Association functional class or a ≥ 25% increase in distance covered on the 6-minute walking test. Secondary endpoints were change in LVEF, septal fla

SUBMITTER: Pujol-Lopez M 

PROVIDER: S-EPMC12800822 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature