Expert Perspectives on a Randomized Controlled Trial Comparing Novel Donor Storage Platforms to Cold-static Preservation for Heart Transplantation.

ABSTRACT:

Background

There is a clinical need for randomized evidence to establish the comparative efficacy of organ preservation techniques for heart transplantation in Canada. In this study we used a survey to evaluate the feasibility and value of a randomized trial comparing cold-static preservation with novel donor storage platforms.

Methods

A validated survey was distributed to 30 members of the Canadian Cardiac Transplant Network, including adult heart failure cardiologists, pediatric cardiologists, and cardiovascular surgeons. Survey sections addressed demographics, clinical scenarios, perceived benefits, barriers, and willingness to participate in a randomized trial.

Results

Twenty-six experts (87%) responded: 65% were adult heart failure cardiologists, 27% were women,

SUBMITTER: Alsaeid R 

PROVIDER: S-EPMC12800825 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature