Real-time magnetic resonance-guided radiofrequency ablation and lesion evaluation in an magnetic resonance-compatible isolated beating pig heart platform.

ABSTRACT:

Background

Interventional cardiovascular magnetic resonance imaging (MRI) offers real-time, radiation-free guidance for complex procedures such as myocardial ablation, marking a promising advance in electrophysiology. However, further development is limited by challenges in magnetic resonance (MR)-compatible instrument testing, MRI sequence validation, and accurate correlation with histopathology, hindered by the limitations of in vivo tissue evaluation.

Objective

This study investigated the feasibility of real-time MR-guided radiofrequency (RF) ablation in an MR-compatible isolated beating pig heart platform and characterized ablation lesions using MRI and histopathology.

Methods

A heart from a pig slaughtered for human consumption was prepared under regulatory guide

SUBMITTER: Hopman LHGA 

PROVIDER: S-EPMC12800846 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature