Novel Bronchoscopy Method for Molecular Profiling of Lung Cancer: Targeted Washing Technique.

ABSTRACT:

Purpose

There have been efforts to find alternative samples other than standard samples of tissue or plasma for mutational analyses for lung cancer patients. However, no other sample or technique has replaced the mutational analyses using standard samples. In this prospective study, we assessed a novel bronchoscopy method, named as targeted washing technique, for detecting the epidermal growth factor receptor (EGFR) mutation.

Materials and methods

A 3.0-mm ultrathin bronchoscope was precisely navigated to the target lung lesion with the assistance of virtual bronchoscopic navigation and fluoroscopy. Once the bronchoscope is placed in front of target lung lesion, 0.9% normal saline was instilled for targeted washing. EGFR testing using targeted washing fluid (TWF) was compare

SUBMITTER: Kim MH 

PROVIDER: S-EPMC12800939 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature