The relationship between fat-soluble vitamins and uterine fibroids: a systematic review.

ABSTRACT:

Background

Uterine fibroids (UF) is a common gynecology tumor that in some cases may require hysterectomy. It is hypothesized that deficiency in fat-soluble vitamins might be a risk factor for UF. The aim of this systematic review was to evaluate the relationship between fat-soluble vitamins and UFs.

Methods

This systematic review was conducted on published articles in PubMed and Web of Science till Feb 2024 using a comprehensive search strategy.

Results

Of the initial 9161 identified articles, 31 (overall population of 55189 participants), including 17 case-control studies, 6 clinical trials, four cross-sectional studies, three cohort studies, and one Mendelian epidemiological study were reviewed. Majority of the studies evaluated the relationship between serum vitam

SUBMITTER: Dashti S 

PROVIDER: S-EPMC12801442 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature