Unveiling the prognostic power of FIB-4 index: a new frontier in heart failure mortality.

ABSTRACT:

Background

The fibrosis-4 (FIB-4) index is valuable in predicting cardiovascular events in individuals with type 2 diabetes. This paper was to ascertain the predictive power of FIB-4 for mortality in patients with heart failure (HF).

Methods

Patient data were sourced from the MIMIC-IV database and allocated to quartiles based on FIB-4 values. All-cause deaths at 30 days, 90 days, and 1 year after patient admission were the endpoints. Cox models, adjusted for multiple factors, were leveraged to examine the link between FIB-4 and mortality in HF patients. Kaplan-Meier (K-M) survival curves were utilized to unveil differences in mortality among different FIB-4 subgroups. Restricted cubic spline (RCS) was adopted to testify the dose-response relationship between FIB-4 and mortal

SUBMITTER: Lu W 

PROVIDER: S-EPMC12801595 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature