Comparative efficacy of different diet modalities on metabolic profiles and liver functions in metabolic dysfunction-associated fatty liver disease: a network meta-analysis.

ABSTRACT:

Background

Metabolic dysfunction-associated fatty liver disease (MAFLD) is a global public health challenge that is primarily managed through lifestyle interventions, particularly diet. This network meta-analysis aimed to thoroughly evaluate the effectiveness of four different dietary patterns: Mediterranean diet (MD), intermittent fasting (IF), Dietary Approaches to Stop Hypertension (DASH), and low-fat diet (LF) in improving liver function and metabolic profiles in adults diagnosed with MAFLD.

Methods

In accordance with the PRISMA guidelines, we conducted a search in PubMed, Embase, Web of Science, the Cochrane Library, ClinicalTrials.gov, and WHO-ICTRP for randomized controlled trials (RCTs) up to Oct. 19, 2025, and registered the study on PROSPERO (CRD42024609524). The C

SUBMITTER: Zou J 

PROVIDER: S-EPMC12801597 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature