Genomic characterization of non-O1, non-O139 Vibrio cholerae causing rare clinical manifestation.

ABSTRACT:

Background

Non-O1, non-O139 Vibrio cholerae is an uncommon cause of pneumonia, particularly following freshwater exposure. Non-O1, non-O139 Vibrio cholerae was identified from bronchoalveolar lavage through culture and quantitative polymerase chain reaction (qPCR) in Hungary. During an epidemiological investigation, the source of infection was traced to a designated bathing site at a lake in Central Hungary, where non-O1,non-O139 Vibrio cholerae was isolated from surface water.

Methods

We conducted whole-genome sequencing and comparative genomic analysis on a clinical isolate (N = 1) and three phenotypically distinct environmental isolates (N = 3). In addition, we reviewed the available literature on pulmonary infections associated with Vibrio cholerae.

Results

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SUBMITTER: Henczko J 

PROVIDER: S-EPMC12801787 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature