Left ventricular deformation and tissue characteristics in hypertrophic cardiomyopathy patients with HFpEF: a CMR study.

ABSTRACT:

Purpose

This study aimed to evaluate left ventricular (LV) deformation and tissue characteristics using cardiac magnetic resonance (CMR) in patients with hypertrophic cardiomyopathy (HCM) and heart failure with preserved ejection fraction (HFpEF), to examine their associations with heart failure status, and to explore the correlations between CMR parameters and the H₂FPEF score.

Methods

This retrospective study included 105 patients with HCM who underwent 3.0-T CMR. Participants were classified into HFpEF (n = 46) and non-HF (n = 59) groups according to the 2019 ESC HFA-PEFF algorithm. Global radial strain (GRS), global circumferential strain (GCS), global longitudinal strain (GLS), and corresponding systolic and early-diastolic strain rates were derived using CMR

SUBMITTER: Liu J 

PROVIDER: S-EPMC12801962 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature