Clinical risk factors and a predictive nomogram for mechanical ventilation in pediatric patients with infection-related plastic bronchitis.

ABSTRACT:

Background

Plastic bronchitis (PB) in children may cause respiratory failure requiring mechanical ventilation (MV), but systematic risk assessments are lacking. This study aimed to identify clinical risk factors for MV in infection-related PB and to develop a predictive nomogram for individualized risk stratification.

Methods

In this retrospective cohort study, pediatric patients diagnosed with infection-related PB at our center between August 2019 and August 2025 were included. Univariate and multivariate logistic regression analyses were performed to identify independent risk factors for MV. A predictive model and nomogram were developed, with discrimination evaluated by area under the receiver operating characteristic curve (AUC) and calibration assessed using bootstrap r

SUBMITTER: Peng H 

PROVIDER: S-EPMC12802196 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature