Dataset Information
MSCohi-O lenses attenuate corneal transplant rejection via HLA-G5 driven Treg cell expansion.
Ontology highlight
ABSTRACT:
SUBMITTER: Li Y
PROVIDER: S-EPMC12802252 | biostudies-literature | 2025 Dec
REPOSITORIES: biostudies-literature
Publications
MSCohi-O lenses attenuate corneal transplant rejection via HLA-G5 driven Treg cell expansion.
BMC ophthalmology 20251208 1
BACKGROUND: Corneal transplantation is a critical approach for some vision loss patients. However, the rejection of human organs severely affects the survival rate of the cornea. In addition, oral or intravenous medication against rejection may have side effects on patients, such as systemic immunosuppression. Therefore, a promising strategy for ocular local medication needs to be designed. On the basis of these findings, we constructed a novel platform, the mesenchymal stromal cell-coating high ...[more]
