RprR is a plant-responsive regulator of exopolysaccharide production, biofilm formation, and virulence in <i>Ralstonia pseudosolanacearum</i>.

ABSTRACT: Ralstonia pseudosolanacearum (Rps), which causes bacterial wilt disease of many crops, must integrate environmental signals to successfully transition from soil to its pathogenic niche in host plant xylem tissue. Mutating a gene encoding a putative sensing/signaling protein had little transcriptomic effect on Rps strain GMI1000 in culture. However, when the mutant grew in tomato, over 180 genes were differentially expressed relative to the wild type. The gene was therefore named rprR for Ralstonia plant-responsive regulator. In planta, the ∆rprR mutant dysregulated genes for diverse traits, including stress response, degradation of phenolic compounds, motility, attachment, and production of extracellular polysacch

SUBMITTER: O'Banion BS 

PROVIDER: S-EPMC12802281 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature