Near-Infrared-II Absorbing Doubly N-Confused Dioxo-Heptaphyrins as Robust Photothermal Conversion Agents.

ABSTRACT: We present the synthesis of a novel meso-aryl-substituted [32]heptaphyrin 1 composed of two confused pyrrole units with a cisoid configuration. Under specific oxidative conditions, the α-carbons of the confused pyrrole units in the precursor were directly linked to yield a hybrid bicyclic compound 2, which integrates distorted corrorin and sapphyrin moieties. Compound 2 possesses a pseudo-annulenoannulene structure along with an emissive character in the near-infrared region. Further chemical oxidation of 1 produces the dioxygenated derivative 1-O₂, transforming into a 30π-conjugation system. The dioxo-heptaphyrin 1-O₂ displays site-selective metal coordination ability within the distorted N4 donor core. The resulting zinc(II) and copper(II) metal complexes, Zn1-O

SUBMITTER: Ito K 

PROVIDER: S-EPMC12802536 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature