Alcohol Use After TIPS Implantation Significantly Increases the Risk of ACLF and Liver-Related Death.

ABSTRACT:

Background

Complications related to portal hypertension (PH) in patients with alcohol-related liver disease (ALD) can be controlled by transjugular intrahepatic portosystemic shunt (TIPS) placement; however, the impact of ongoing alcohol use (AU) after TIPS remains scarcely investigated.

Methods

ALD patients undergoing TIPS implantation between 2000 and 2022 were included. Laboratory/demographic parameters and clinical events/outcomes were compared per post-TIPS AU status and to a group of n = 55 decompensated ALD patients with ongoing AU who did not receive TIPS.

Results

Overall, 248 TIPS patients (78.2% male; median age: 55.5 years; ascites: 69.8%; median MELD: 12), including 90 (36.3%) with ongoing AU after TIPS were included. AU post-TIPS was independently associa

SUBMITTER: Schwarz C 

PROVIDER: S-EPMC12802573 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature