Early Neurological Deterioration following acute stroke: association with reperfusion therapies and National Institutes Of Health Stroke Scale score.

ABSTRACT: Early Neurological Deterioration (END) following acute stroke is associated with worse long-term functional outcomes. END is poorly defined and its relationship to reperfusion therapies is not fully understood. NIHSS is commonly used to risk-stratify and identify END following acute stroke however its relationship to END is relatively unexplored. The electronic health record of 933 stroke patients admitted to the Hyperacute Stroke Unit at King's College Hospital in 2022 were manually reviewed for END up to 14-days post stroke to: (1) characterize etiology and risk factors associated with END following acute stroke, and (2) evaluate the association between END, reperfusion therapy and NIHSS. Age, sex and co-morbidity were not associated with END, whereas reperfusion therapy was associated w

SUBMITTER: Yu TB 

PROVIDER: S-EPMC12802648 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature