Linking evidence for targeted blood biomarkers in post-stroke cognitive impairment and dementia.

ABSTRACT: With improvements in acute stroke treatment and more patients surving the acute stroke period, the identification and prognostication of post-stroke disability is paramount. Post-stroke cognitive impairment and dementia (PSCID) severely impacts the morbidity and mortality of stroke survivors. While clinical factors and imaging are useful in identifying patients at risk for PSCID, blood-based biomarkers are sorely needed to provide cost-effective identification and prognostication for patients at greatest risk. Furthermore, blood-based biomarkers can inform the biologic basis for PSCID and lead to potential treatment targets. This narrative review attempts to summarize currently available research on the use of fluid biomarkers to measure and quantify PSCID using a framework proposed for us

SUBMITTER: Hong J 

PROVIDER: S-EPMC12802771 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature