Mechanisms of pediatric ischemic strokes in COVID-19: a systematic review.

ABSTRACT:

Background

Coronavirus disease 2019 (COVID-19) has been shown to cause vasculopathic and hemostatic derangements predisposing to cerebrovascular and thrombotic disorders in adults. Data in children, however, are limited to case reports and series. Given the unique risk factors and potential pathomechanisms in children, it is imperative to characterize stroke in children with COVID-19. Understanding these mechanisms is essential in drafting an appropriate management protocol to improve outcomes in a population where stroke carries higher disability-adjusted life years.

Methods

A systematic literature search was done in MEDLINE, EMBASE, Web of Science and Google Scholar using the terms "pediatric ischemic stroke," "cerebral sinovenous thrombosis," "SARS-CoV-2," and "COVID-19."

SUBMITTER: Layug EJV 

PROVIDER: S-EPMC12802804 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature