Evolving landscape of methicillin-resistant Staphylococcus pseudintermedius: the emergence of new epidemic waves across Europe, Asia and North America.

ABSTRACT:

Objective

This study aims to identify spatiotemporal variations in clonal diversity and antimicrobial resistance of methicillin-resistant Staphylococcus pseudintermedius (MRSP).

Materials and methods

A PubMed search (June 2016-December 2023), combined with data from PubMLST and a previous review (September 2007-May 2016), identified 2654 isolates. Multinomial logistic regression (MLR) and Bayesian regression models (BRMs) were used to assess associations between clonal complexes (CCs) and variables (sample type, continent and period), with MLR results feeding into the BRM.

Results

A shift in MRSP clonal structure was observed after 2013. A decline in the prevalence of historically dominant lineages, such as CC71 in Europe, CC68 in North America and CC45 in Asia, coinc

SUBMITTER: Giarratana LR 

PROVIDER: S-EPMC12802899 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature