<i>Plasmodium vivax</i> Malaria Relapse Risk Depends on Transmission Intensity: Evidence From a Longitudinal Study in Northwest Thailand.

ABSTRACT:

Background

In northwest Thailand, the provision of radical cure to prevent relapses of Plasmodium vivax malaria has decreased P vivax caseloads and decreased transmission. While malaria control measures were increased, we performed a prospective observational rolling cohort study to describe the changing incidence of P vivax malaria and the associated recurrence rates.

Methods

Healthy nonpregnant glucose-6-phosphate dehydrogenase-normal volunteers who had symptomatic P vivax infection in the previous 12-24 months, but who had not received radical cure, were recruited. Supervised primaquine was given daily for 14 days (0.5 mg base/kg/day). Participants were followed 4 and 8 weeks later, then every 2 months until they developed symptomatic or asympt

SUBMITTER: Chu CS 

PROVIDER: S-EPMC12803024 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature