Cortical deviance detection represents a canonical difference signal.

ABSTRACT: Context modulates neural processing of sensory stimuli. Neural responses are suppressed to stimuli that are typical in their context and augmented to stimuli that deviate from their context. The latter has been conceptualized as a "prediction error", which can serve to enhance the salience, direct attention, or support learning about behaviorally relevant events. Predictive coding theories posit that prediction errors act to signal the difference between internal predictions and actual sensory input, yet most paradigms simultaneously alter both predictions and input, so cannot test for a true difference signal. Increased neural responses to deviants could, instead, encode generalized surprise or augmented bottom-up signaling. Here we compare neural responses to auditory stimuli across oddb

SUBMITTER: Hockley A 

PROVIDER: S-EPMC12803178 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature