Unravelling the epidemiological and dispersal dynamics of the 2024-2025 chikungunya virus outbreak on Reunion island.

ABSTRACT: Réunion island just experienced a massive chikungunya virus outbreak in 2024-2025, with more than 54,000 confirmed cases. This is the second major chikungunya outbreak on the island, following the first one that peaked 20 years ago. It has been assessed that this new outbreak finds its origin in a single introduction event into the island, offering a unique opportunity to exploit viral genomic data to understand the epidemiological and dispersal dynamics of the introduced transmission chain. We sequenced >3,000 near-full viral genomes collected during the course of the epidemic. Harnessing this genomic dataset, we used a set of phylodynamic and phylogeographic approaches to unravel the paths taken by the transmission chain and the external factors having impacted its dynamics on the island

SUBMITTER: Frumence E 

PROVIDER: S-EPMC12803385 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature