Identifying Extended-Release Naltrexone Treatment for Opioid Use Disorder in US Medicaid Data.

ABSTRACT:

Purpose

Extended-release naltrexone (XR-NTX, monthly injection) is used to treat opioid use disorder (OUD). In claims data, XR-NTX may be identified by drug or procedure codes. In the US, Medicaid is a predominant payer of OUD treatment and differences in state Medicaid policies may produce variation in XR-NTX coding. We aimed to describe documentation of XR-NTX in multi-state Medicaid data.

Methods

Using 2016-2019 National Medicaid data (TAF) from 26 states, we identified individuals with an XR-NTX specific drug or procedure code and evidence of OUD during ≥ 5 months continuous Medicaid enrollment (N = 26 169). At the individual's first observed XR-NTX treatment, we described state-level variation in the types of codes, file source, and presence of procedure codes for injec

SUBMITTER: Ross RK 

PROVIDER: S-EPMC12803443 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature