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Effects of hypoxic training interventions on cardiometabolic health of adults with overweight and obesity: A systematic review and meta-analysis.


ABSTRACT: Obesity rates have surpassed underweight globally, increasing the burden of cardiometabolic complications on healthcare systems. Hypoxic training has emerged as a potential intervention to improve cardiometabolic health in adults with obesity, but evidence remains inconclusive. This systematic review and meta-analysis evaluated whether hypoxic training is more effective than normoxic training in this context. A systematic search of PubMed, Web of Science, and Cochrane Library (up to June 2025) identified randomised controlled trials comparing hypoxic and normoxic training in adults with overweight or obesity. Outcomes included glucose homeostasis, lipid profile, and blood pressure. Subgroup, moderation, and sensitivity analyses were also conducted to explore sources of heterogeneity and as

SUBMITTER: Gatti A 

PROVIDER: S-EPMC12803568 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature