Heart failure in patients with a systemic right ventricle: A multicentre study with long-term follow-up.

ABSTRACT:

Aims

Adult patients with transposition of the great arteries (TGA) and an systemic right ventricle (sRV) are at risk for heart failure (HF). In this study, we investigated risk factors for HF hospitalization and developed a novel risk stratification tool to optimize risk prediction for clinical practice.

Methods and results

In this international multicentre study, 522 patients with TGA and an sRV, without history of HF hospitalization, were followed retrospectively for a median of 17.9 years (interquartile range [IQR] 12.9-22.1). HF hospitalization was defined as a hospital admission for HF signs and symptoms with initiation or increase of HF medication. Predictors for HF hospitalization were established using a Cox regression analysis and were used to build a 10-year risk s

SUBMITTER: Ansari Ramandi MM 

PROVIDER: S-EPMC12803627 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature