Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Systemic Cancer Therapy: ASCO Guideline Update.

ABSTRACT:

Purpose

To update the ASCO guideline (2018) on the practical assessment and management of age-associated vulnerabilities in older patients undergoing systemic cancer therapy.

Methods

An Expert Panel conducted a systematic review to identify relevant randomized clinical trials (RCTs), systematic reviews, and meta-analyses from January 2016 to December 2022.

Results

A total of 26 publications met eligibility criteria and form the evidentiary basis for the update.

Recommendations

The Expert Panel reiterates its overarching recommendation from the prior guideline that geriatric assessment (GA), including all essential domains, should be used to identify vulnerabilities or impairments that are not routinely captured in oncology assessments for all patients over 65 y

SUBMITTER: Dale W 

PROVIDER: S-EPMC12803700 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature