Preliminary Investigation and Safety Profile of a Novel Hybrid Filler (Hyaluronic Acid-Calcium Hydroxylapatite) in Asian Facial Rejuvenation.

ABSTRACT: Injectable fillers, such as hyaluronic acid (HA)-based fillers and calcium hydroxylapatite (CaHA) collagen stimulators, have been used to replenish lost volume by physically filling gaps or stimulating collagen synthesis. A commercially available hybrid filler combining HA and CaHA in a new gel-form collagen stimulator has yet to be extensively studied in an Asian population. This was a case series of patients attending 2 centers in Hong Kong between August 2023 and February 2024 to document the safety of HA-CaHA in Asian patients. Outcomes included patients' overall satisfaction with the treatment experience, based on the Global Aesthetic Improvement Scale assessment and treatment-emergent adverse events reported after treatment at the 3- and 6-month follow-ups. Twenty-five Chinese patien

SUBMITTER: Chang NWM 

PROVIDER: S-EPMC12803714 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature