A multi-centre performance evaluation of a commercially developed liquid biopsy for the earlier detection of brain tumours.

ABSTRACT:

Background

Delayed diagnosis of brain cancer leads to two-thirds of patients receiving a diagnosis only after presenting to the emergency department with more severe symptoms or neurological deficits. A simple, rapid, liquid biopsy implemented in primary care could enable more efficient triage of patients with non-specific symptoms potentially related to brain cancer, prioritising patients for urgent brain imaging, and accelerating diagnosis.

Patients and methods

Presented is the international, multi-centre, observational Early and tiMely detection of BRAin CancEr (EMBRACE) study. Patients were prospectively recruited across seven sites in Europe, from the United Kingdom, Belgium, Sweden and Switzerland. The target population consisted of patients with symptoms potentially a

SUBMITTER: Brennan PM 

PROVIDER: S-EPMC12804056 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature