Endoscopic repair of large dural defects in transsphenoidal surgery by suturing acellular dermal matrix graft with the dura: a technical note.

ABSTRACT:

Objective

To introduce acellular dermal matrix (ADM) suturing as a novel repair method for intraoperative high-flow cerebrospinal fluid (CSF) leakage during transsphenoidal surgery (TSA), aiming to replace autologous fat/fascia lata grafts and reduce surgical morbidity.

Methods

Five patients (2 invasive pituitary adenomas, 2 craniopharyngiomas, 1 epidermoid cyst) underwent total sellar/suprasellar tumor resection and presented intraoperative high-flow CSF leakage. ADM grafts were tailored to dural defects and sutured directly to native dural edges. Outcomes included repair integrity, operative efficiency, and postoperative complications (CSF leakage, infection).

Results

All cases achieved dural closure without autologous tissue harvesting. Mean operative time was redu

SUBMITTER: Quan W 

PROVIDER: S-EPMC12804199 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature