Hemodynamics-guided therapy for hypertensive disorders of pregnancy: a systematic review.

ABSTRACT:

Objective

Despite on-going research into the underlying pathology of hypertensive disorders in pregnancy, maternal mortality is hardly decreasing. Current antihypertensive therapy is aimed at controlling symptoms and preventing severe courses of pregnancy. Traditional management focuses on blood pressure (BP) control, but does not consider individual hemodynamic variations. Hemodynamically guided therapy offers a personalized approach that can improve BP control and outcomes by treating the underlying pathophysiology. The aim of this review is to provide an overview of hemodynamically guided antihypertensive therapy in hypertensive disorders of pregnancy and to present the results of recent intervention trials in this area.

Methods

Literature searches were conducted in the e

SUBMITTER: Loheit AC 

PROVIDER: S-EPMC12804288 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature