Dataset Information
Upregulated ARMCX1 suppresses nasopharyngeal carcinoma progression by promoting TRIM21-mediated β-catenin degradation.
Ontology highlight
ABSTRACT:
SUBMITTER: Hu Z
PROVIDER: S-EPMC12804310 | biostudies-literature | 2026 Jan
REPOSITORIES: biostudies-literature
Publications
Upregulated ARMCX1 suppresses nasopharyngeal carcinoma progression by promoting TRIM21-mediated β-catenin degradation.
Cellular oncology (Dordrecht, Netherlands) 20260114 1
BACKGROUND: Armadillo repeat-containing X-linked 1 (ARMCX1) has been reported to exhibit a suppressive effect in a variety of solid tumors. However, neither its biological role nor its potential mechanism of action has yet been reported in nasopharyngeal carcinoma (NPC). METHODS: Immunohistochemical staining of an NPC tissue microarray was performed to evaluate the clinicopathologic association between ARMCX1 and NPC patients. The effect of ARMCX1 on the growth, migratory, and invasive capacitie ...[more]