Overall survival following treatment of central nervous system meningeal melanocytomas: Insights from the national cancer database (NCDB).

ABSTRACT:

Introduction

Central nervous system (CNS) melanocytomas are rare, pigmented tumors derived from leptomeningeal melanocytes. Although generally benign, they can exhibit locally aggressive behavior and recur. Despite increasing recognition, data on their clinical outcomes and optimal management remain limited.

Research question

This study aimed to evaluate the survival outcomes of patients with CNS melanocytomas, using a large national registry, and to explore the prognostic relevance of tumor location and treatment modalities.

Methods

We queried the National Cancer Database (NCDB) for cases of CNS melanocytomas diagnosed between 2004 and 2017. Patient demographics, tumor characteristics, treatment details, and survival outcomes were collected. Kaplan-Meier survival ana

SUBMITTER: El-Hajj VG 

PROVIDER: S-EPMC12804625 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature