Uncovering oscillatory dysregulation associated with suicide risk in major depressive disorder: a narrative review.

ABSTRACT: Neural oscillations have emerged as critical markers of cognitive and emotional states, offering valuable insights into psychiatric disorders. Given the potential suicide risk in patients with major depressive disorders (MDD), its underlying neurophysiological associations need to be further elucidated. This review aimed to comprehensively examine the complex relationships between neural oscillations and suicide risk in MDD. We performed a detailed analysis of electrophysiological phenomena reported in studies investigating suicide risk within depressive populations, consisting of event-related potentials (ERPs) and neuronal oscillations across theta, delta, alpha, beta, and gamma frequency bands. Notably, reduced P300 amplitude, associated with cognitive dysfunction, was observed with ele

SUBMITTER: Dai Z 

PROVIDER: S-EPMC12804689 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature