Comparative phenotypic analysis of the Bordetella parapertussis isolate chosen for genomic sequencing.

ABSTRACT: The genomes of three closely related bordetellae are currently being sequenced, thus providing an opportunity for comparative genomic approaches driven by an understanding of the comparative biology of these three bacteria. Although the other strains being sequenced are well studied, the strain of Bordetella parapertussis chosen for sequencing is a recent human clinical isolate (strain 12822) that has yet to be characterized in detail. This investigation reports the first phenotypic characterization of this strain, which will likely become the prototype for this species in comparison with the prototype strains of B. pertussis (Tohama I), B. bronchiseptica (RB50), and other isolates of B. parapertussis. Multiple in vitro and in vivo assays distinguished each species. B. parapertussis was mo

SUBMITTER: Heininger U 

PROVIDER: S-EPMC128047 | biostudies-literature | 2002 Jul

REPOSITORIES: biostudies-literature