Prognostic model and U-shaped SBP-risk correlation in unstable pelvic fractures with TBI.

ABSTRACT: Patients with unstable pelvic fractures combined with traumatic brain injury (TBI) present complex conditions, with pathophysiological contradictions in clinical treatment between limited fluid resuscitation and maintenance of cerebral perfusion pressure. A retrospective analysis was conducted on 204 patients with unstable pelvic fractures combined with TBI between January 1, 2010, and May 31, 2025. A Nomogram model was constructed via LASSO and multivariate logistic regression, with simultaneous development of an interpretable machine learning prediction model. Results identified shock, abnormal systolic blood pressure (SBP), non-surgical management, and prolonged coagulation time as independent poor prognosis risk factors. The Nomogram constructed using SBP, shock, pelvic fracture surger

SUBMITTER: Du S 

PROVIDER: S-EPMC12804734 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature