Genome-wide characterization of WD40 repeat proteins in cucumber reveals their functional roles in stress response and parthenocarpy.

ABSTRACT: WD40 repeat proteins play crucial roles in various biological processes, including stress responses, development, and signaling. In this study, we identified and characterized 142 WD40 genes (CsWDR) in cucumber (Cucumis sativus), using the Hidden Markov Model to detect WD40 domains. These genes exhibited considerable variation in protein length and domain structure, with some containing additional functional domains such as UTPB, zinc finger, and F-box. Phylogenetic analysis revealed seven distinct clusters of CsWDR proteins, suggesting functional divergence, including roles in stress tolerance. Gene Ontology analysis highlighted their involvement in metabolic processes, stress responses, and protein binding, with most localized to the nucleus. Expression profiling revealed distinct patter

SUBMITTER: Zhang T 

PROVIDER: S-EPMC12804792 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature