Optimization of Kidney Disease: Improving Global Outcomes Criteria for AKI for Pediatric Population.

ABSTRACT:

Introduction

Accurate detection and staging of acute kidney injury (AKI) is important in clinical practice to aid timely management. The main purpose of this study is to establish a pediatric version of Kidney Disease: Improving Global Outcomes (KDIGO, pKDIGO) criteria for pediatric population.

Methods

The pKDIGO criteria defined AKI following the principles of KDIGO, in which the threshold of absolute increase in serum creatinine (SCr) or absolute decrease in estimated glomerular filtration rate (GFR, eGFR) to diagnose AKI has been revised to eliminate the impacts of age and sex of children. Then, AKI defined by pKDIGO were compared with that defined by KDIGO, modified KDIGO (mKDIGO), pediatric reference change value optimized for AKI in children (pROCK), and pediatric Risk

SUBMITTER: Zhang C 

PROVIDER: S-EPMC12805013 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature