Residual Cardiovascular Biomarkers After Medical Therapy and Their Prognostic Implications Following Percutaneous Coronary Intervention.

ABSTRACT:

Background

Despite medical therapy, atherothrombotic events remain common in high-risk patients with coronary artery disease.

Objectives

The purpose of this study was to evaluate the association between atherothrombotic biomarkers and outcomes in patients with coronary artery disease who are undergoing percutaneous coronary intervention (PCI).

Methods

Biomarkers including lipid profile (low-density lipoprotein cholesterol and triglycerides), inflammation (high-sensitivity C-reactive protein [hs-CRP]), platelet reactivity (P2Y12 reaction unit), and coagulation (fibrinogen) were measured on admission and at 1 month following medical therapy post-PCI (n = 2,789). The primary endpoint was major adverse cardiovascular events, defined as a composite of cardiovascular death,

SUBMITTER: Cho JH 

PROVIDER: S-EPMC12805105 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature