Frailty and Age as Predictors of Mortality in Acute Myocardial Infarction Complicated by Cardiogenic Shock.

ABSTRACT:

Background

Cardiogenic shock is a serious complication of acute myocardial infarction (AMICS) with an in-hospital mortality rate of approximately 50%. Frailty is associated with poor outcomes in general but has been poorly investigated in AMICS.

Objectives

The purpose of this study was to evaluate the independent and combined effects of frailty and age on mortality in AMICS patients.

Methods

We conducted a retrospective observational study using the RETROSHOCK cohort, including 1,716 AMICS patients admitted to 2 tertiary university hospitals in Denmark (2010-2017). Frailty was assessed using the Hospital Frailty Risk Score, with frailty defined as a score ≥5. Patients were further stratified by age ≥70 and <70 years old. In a separate analysis, age was categorized int

SUBMITTER: Ahmadzai MW 

PROVIDER: S-EPMC12805165 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature