Xylanase and Bacillus subtilis PB6 modulate microbiota and short-chain fatty acid profiles in broilers under necrotic enteritis-challenge.

ABSTRACT: Necrotic enteritis (NE) is a major poultry disease affecting profitability. Managing NE has become harder due to restrictions on in-feed antibiotics, which traditionally support gut health and production in broilers. To address this, a study was conducted to evaluate the effect of xylanase (Xy) and Bacillus subtilis (Pb) supplementation in a corn-soybean-based diet on the intestinal health of broiler chickens under NE challenge. A total of 630-d-old mixed-sex Cobb 500 broiler chicks were assigned to a 2 × 2 + 1 factorial design, giving five treatments: NE challenge without additives (CC); NE challenge with Xy (0.03%) (Xy); NE challenge with Pb (0.05%) (Pb); NE challenge with Xy (0.03%) and Pb (0.05%) (Xy+Pb); and non-challenge birds without additives (NC). NE challenge significantly increa

SUBMITTER: Khairunnesa M 

PROVIDER: S-EPMC12805170 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature