Vascular Aging, Cardiovascular-Kidney-Metabolic Syndrome, and Cardiovascular Risk: The Northern Shanghai Study.

ABSTRACT:

Background

The role of vascular aging in cardiovascular-kidney-metabolic (CKM) syndrome and its associated cardiovascular risk remains unclear.

Objectives

This study aims to explore the relationship between CKM syndrome, vascular aging, and cardiovascular risk.

Methods

This analysis was based on the Northern Shanghai Study (2013-2022), a prospective study of community-dwelling elderly Chinese. CKM syndrome was classified into 5 stages (0-4) according to the American Heart Association's presidential advisory. Participants with cardiovascular disease (ie, CKM stage 4) were excluded. Vascular aging was defined as a carotid-femoral pulse wave velocity≥10 m/s. Multivariable-adjusted Cox proportional hazard models were used to evaluate the associations of CKM syndrome and v

SUBMITTER: Shi J 

PROVIDER: S-EPMC12805181 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature