Sleep alterations in substance use disorders: a systematic review and meta-analysis.

ABSTRACT:

Background

Sleep disturbances are common in individuals with substance use disorders (SUDs), often persisting beyond initial abstinence and hindering recovery. However, the underlying sleep abnormalities warrant further investigation, particularly given mixed findings regarding specific substances.

Methods

This systematic review and meta-analysis aimed to identify sleep-related abnormalities associated with alcohol (AUD), benzodiazepine (BUD), cannabis (CaUD), cocaine (CoUD), methamphetamine (MUD), nicotine (NUD), and opioid (OUD) use disorders. We systematically searched Embase, PsycINFO, PubMed, Scopus, and Web of Science until November 2025, following a pre-registered protocol (PROSPERO: CRD42024531160).

Findings

We conducted a systematic review of 43 eligible publ

SUBMITTER: Oliva HNP 

PROVIDER: S-EPMC12805338 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature