A rare case of left ventricular cardiac rupture in the acute phase of takotsubo syndrome.

ABSTRACT: Takotsubo syndrome (TTS), often triggered by emotional or physical stress, is characterized by transient left ventricular dysfunction that mimics acute coronary syndrome. We present a case involving an 85-year-old woman with a history of atrial fibrillation who developed sudden severe chest pain during sleep. Initial evaluation suggested ST elevation myocardial infarction; however, emergency coronary angiography revealed patent coronary arteries, leading to a diagnosis of TTS. Immediately after angiography, the patient experienced sudden loss of consciousness, which resulted in death with diminished circulating plasma volume. Autopsy confirmed mid-antero-septal wall rupture with massive left pleural thrombus, suggesting cardiac rupture due to TTS as the cause of death. Our case represents

SUBMITTER: Iwata S 

PROVIDER: S-EPMC12805424 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature