Incidence of AIDS-defining Illness by Cancer Status in an Observational Study among Medicaid Beneficiaries Living with HIV in the United States, 2001 - 2015.

ABSTRACT:

Background

Malignant neoplasms remain one of the leading morbidities and causes of death among people with HIV (PWH). Prior research suggests that certain cancer treatments may have deleterious effects on the immune system.

Setting

We quantified the relationship between non-AIDS-defining cancers (NADC) and the development of a new AIDS-defining illness (ADI) among PWH in Medicaid. We assembled a cohort of 154,493 Medicaid beneficiaries aged 18-64 with HIV from 14 US States between 2001-2015, with no evidence of a prevalent ADI or cancer.

Methods

We estimated incidence rates of first ADI among PWH who did and did not develop NADC. NADC status was time-updated, allowing individuals to contribute person-time before and after cancer diagnosis. We compared rates across NAD

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC12805858 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature