Determinants of subclinical leprosy among household contacts in Indonesia: serological and socio-demographic factors.

ABSTRACT:

Background

Leprosy remains a public health challenge in Indonesia, which ranks third globally after India and Brazil. Subclinical infection among household contacts contributes to ongoing transmission, as individuals infected with Mycobacterium leprae (M. leprae) without symptoms may serve as undetected reservoirs. This study investigated serological and sociodemographic determinants associated with subclinical M. leprae infection among household contacts of leprosy patients in Tangerang, Indonesia.

Methods

A cross-sectional study was conducted in 2020 among 320 household contacts of confirmed leprosy index cases recruited through purposive sampling. Anti-Phenolic Glycolipid-1 (PGL-1) IgM antibodies were detected using an in-house enzyme-linked immunosor

SUBMITTER: Khariri K 

PROVIDER: S-EPMC12805909 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature