Impact of Diverse Clinical Characteristics on Survival Benefit of Liver Transplantation.

ABSTRACT:

Background

Liver transplantation (LT) is offered as a life-saving treatment to those with end-stage liver disease. There has recently been much interest in considering the survival benefit of transplant when prioritizing patients for transplant. In this study, we aimed to measure the survival benefit of LT across various patient demographics by measuring the number of life-years gained after LT.

Method

In this study, 101,770 patients were included from the Scientific Registry of Transplant Recipients (SRTR) transplanted between 2003 and 2021. The survival benefit of LT was calculated using restricted mean survival time (RMST) in the next 16 years post-transplant. Cox proportional hazard models and Weibull models were employed to quantify the impact of various predictors on s

SUBMITTER: Alim M 

PROVIDER: S-EPMC12805940 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature